2nd MASIR Conference
Measuring Antigen-Specific Immune Responses
Santorini, Greece, 14-17 June 2006

MASIR Conference will be held at the Nomikos conference site, which is located within walking distance from the hotels.

PROGRAMME
(you can download the programme in PDF form HERE)

Wednesday, 14 June 2006

TIME
PROGRAMME DESCRIPTION
14.00 - 22.00
Arrive: Hotel check-in and Meeting Registration
20.00 - 22.00
Light snacks & Social Gathering

 

Thursday, 15 June 2006

TIME
PROGRAMME DESCRIPTION
8.00 - 9.00
Poster Setup
9.00 - 9.15
Introduction
9.15 - 11.00
Session 1: Novel approaches - Chairman: M. Roederer (US)
 
Design and use of conditional class I MHC ligands
(Ton Schumacher [Amsterdam, NL])
 
Molecular and Functional Profiling of Immune Responses Using a pMHC Cellular Microarray
(Daniel Chen [Stanford, CA])
 
A lymphocyte-antigen array approach for microdissection of the functional cellular immune response
(Giusi Li Pira [Genoa, I])
11.00 - 11.30
Break (coffee and tea at the exhibits) and poster viewing
11.30 - 13.00
Session 2: Antigen-specific T Cells in HIV - Chairman: R. Koup (US)
 
New approaches for assessing antigen-specific T cell responses (V. Maino [US]) - Sponsored by BD Biosciences
 
Functional and physical effects of altered CD8 coreceptor engagement by peptide-MHC class I molecules
(David Price [Bethesda, MD])
 
HIV-specific T cell responses in acute subtype C infection
(Clive Gray [Johannesburg, RSA])
 
BD Biosciences Tutorial: Analysis of protein phosphorylation and cellular signaling events by flow cytometry.
 
Break (coffee and tea at the exhibits) and poster viewing
17.30 - 19.00
Session 3: Parasites - Chairman: U. Krzych (US)
 
Analysis of the pathogenic T cell response in schistosomiasis
(Miguel Stadecker [Boston, MA])
 
Role and antigen specificity of natural Treg during parasitic infections
(Yasmine Belkaid [Bethesda, MD])
 
Protective immunity against malaria: parasites and proteins; antigen specificities and memory responses
(Ursula Krzych [Silver Spring, MD])
19.00 - 19.30
Break (coffee and tea at the exhibits) and poster viewing
19.30 - 21.00
Session 4: Tuberculosis - Chairman: F. Kern (D)
 
Measuring antigen specific T cell responses in tuberculosis reveals 25 novel antigens encoded by genes of the dormancy regulon of Mycobacterium tuberculosis, as targets during latency
(Tom Ottenhoff [Leiden, NL])
 
γδ-T lymphocytes and their role in immune response against Mycobacterium tuberculosis
(Francesco Dieli [Palermo, I])
 
Effector mechanisms of TB-specific CD8+ T cells
(Steffen Stenger [Erlangen, D])
21.00 - 23.00
Poster Session I (odd-numbered posters)
Buffet Dinner
Exhibits

 

Friday, 16 June 2006

TIME
PROGRAMME DESCRIPTION
8.30 - 9.15
Technical workshop I: MASIR: validation of phenotypic assays
(Mike Keeney [London, ON])
9.30 - 11.00
Session 5: Autoimmunity & Tumor Immunology
 
T-cell autoreactivity to islet antigens in type 1 diabetes
(Bart Roep [Leiden, NL])
 
Identification of dominant T cell clones strongly responding to tumor antigens in melanoma patients
(D. Speiser [CH])
 
TCR gene therapy of leukemia
(H. Stauss [UK])
11.00 - 11.30
Break (coffee and tea at the exhibits) and poster viewing
11.30 - 13.00
Session 6: Antigen-Specific B & T cells - Chairman: T. Ottenhoff (NL)
 
Prompt and sustained protection against lethal viral disease induced by an improved adenoviral vaccine
(J. Christensen [DK]) - Sponsored by Dako
 
Antigen-specific B cells and plasma cells
(A. Radbruch [D])
 
Poster P24: Decreased specific CD8+ T-cell cross-reactivity of antigen recognition following vaccination with Melan-A peptide
(V. Appay [CH])
 
Poster P43: Detection and characterization of CD4+ viral, vaccine-induced and autoimmune-specific T cells using MHC-peptide arrays
(C. Walker [US])
13.00-15.00
Dako Tutorial: MHC Dextramers in practical use (how to optimize your results).
16.00 - 17.00
Break (coffee and tea at the exhibits) and poster viewing
17.00 - 19.30
Session 7: Antigen-specific T cells: SCT & infections
 
Immunotherapy with donor lymphocytes following allogeneic stem cell transplantation
(Shimon Slavin [Jerusalem, IL])
 
Functional T cell immunity in allogeneic stem cell transplantation
(Krishna Komanduri [Houston, TX]
 
Poster P4: Characterization of CD8+ T cell responses to
dominant and subdominant epitopes in subtype
C HIV-1 infected individuals
(V. Morafo [ZA])
 
Poster P61: Protection against Leishmania major following
vaccination with a recombinant adenovirus is
determined by the quality rather than the
magnitude of the Th1 response
(P. Darrah [US])
19.00 - 19.30
Break (coffee and tea at the exhibits) and poster viewing
19.30 - 21.00
Session 8: Biology and specificity of NK and NKT lymphocytes - Chairman: L. Lanier (US)
 
Control of innate immunity by DAP12-associated immune receptor
(Lewis Lanier [San Francisco, CA])
 
NK cells and tumor recognition
(Cristina Bottino [Genoa, I])
 
NKT cells sustain B cell memory
(Sergio Abrignani [Milano, I])
21.00 - 23.00
Poster Session II (even-numbered posters)
Buffet Dinner
Exhibits

 

Saturday, 17 June 2006

TIME
PROGRAMME DESCRIPTION
8.30 - 9.15
Technical workshop II: MASIR: validation of functional assay
(Mario Roederer [Bethesda, MD])
& (Stephen De Rosa [US])
9.30 - 11.00
Session 9: Herpes viruses - Chairman: F. Manca (I)
 
T cell responses to virus infection : lessons from Epstein-Barr virus
(Alan Rickinson [Birmingham, UK])
 

Immunogenic open reading frames of HCMV: analysis of T Cell responses in naturally infected humans
(Andrew Sylwester [Portland, OR])

 
Poster P27: Differing phenotypic and functional profiles of
HIV- and CMV pp65-specific CD4+ T cells
( J. Casazza [US])
 
Poster P31: Profound loss of IL2 secretion and proliferation of HCV-specific T cells in HIV-1 co-infection
(V. Dutoit [CH])
11.00 - 11.30
Break (coffee and tea at the exhibits) and poster viewing
11.30 - 13.00
Session 10: T-cell adoptive immunotherapy & New Technologies - Chairman: G. Li Pira (I)
 
Epstein-Barr virus
(Tanzina Haque [London, UK])
 
Cell transfer therapy for patients with cancer
(Mark Dudley [Bethesda, MD])
 
Poster P42: Monitoring T cell-mediated cytotoxicity using the fluorescent antigen-transfected target cellcytotoxic T lymphocyte assay
(C. van Baalen [NL])
 
Poster P57: Primary human immune responses in vitro: A tool to screen immunogens and adjuvants for human use
(G. Lewis [US])
13.00 - 17.30
Break (coffee and tea at the exhibits) and poster viewing
17.30 - 19.00
Session 11: MASIR and vaccination - chairman: A. Rickinson (UK)
 
The future of immunogenicity measurements for testing vaccine efficacy: quantity & quality
Mario Roederer [Bethesda, MD]
 
Toll-like receptor ligands influence the magnitude and quality of T cell responses
Bob Seder [Bethesda, MD]
 
Parsing the immunology of Tuberculosis in the context of vaccine design
Mark Doherty [Copenhagen, DK]
 
Unraveling immunologic memory with flow cytometry
Louis Picker [Portland, OR]
20.15 - 23.00
Gala Dinner
Gather at Nomikos Conference center
buses to Santos Winery depart at 20:30

 

Sunday, 18 June 2006

TIME
PROGRAMME DESCRIPTION
 
DEPART