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Wednesday, January 26 |
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14:00
– 22:00 |
Arrive:
Hotel check-in and Meeting Registration |
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20:00
– 22:00 |
Light
snacks & Social Gathering |
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Thursday (8:00 – 17:00), January 27 |
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08:00 |
Poster
setup (Odd-numbered posters) |
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08:30
– 10:10 |
Session 1:
T-Lymphocyte Subsets and Differentiation (Part I) |
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Chairman:
M. Roederer (US) |
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R.
Van Lier (NL): |
Molecular
basis of CD8+ T cell subset differentiation |
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M.
Wills (UK): |
Selection
of the virus-specific CD8+ T cell repertoire following Primary Human
Cytomegalovirus (HCMV) infection: TCR affinity and CD45RA+ CD28- memory
cells. |
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D.
van Baarle (NL): |
Loss
of CMV-specific CD4+ cytokine production and proliferative capacity during
the course of HIV-infection is indicative for progression to CMV-End Organ
Disease |
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10:10
– 10:30 |
Break
(coffee and tea at the exhibits) and poster viewing |
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10:30
– 11:30 |
Session 1: T-Lymphocyte Subsets and Differentiation (Part
II) |
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Chairman:
M. Roederer (US) |
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S.
Rowland-Jones (UK): |
HIV-specific
CTL: differentiation state and cytokine |
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A.
Scheffold (D): |
High-sensitivity
immunofluorescence to detect specific peptide presentation at physiologically
relevant quantities |
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14:00
– 16:00 |
BD
Biosciences Tutorial: Analysis of protein
phosphorylation and cellular signaling events by flow cytometry. |
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16:00
– 17:00 |
Poster
Viewing (coffee and tea at the exhibits) |
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Thursday (Evening), January 27 |
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17:00
– 19:30 |
Session 2:
Cancer and New Technologies |
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Chairman:
J. Gratama (NL) |
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(Poster) |
M.
Streitz (D): |
Systematic
identification of T-cell epitopes in the human Cytomegalovirus proteome using
spot-synthesized peptides |
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(Poster) |
C.
Prussin (US): |
Improved
detection of allergen specific T cell cytokine responses using
carboxyfluorescein succinimidyl ester enhanced T cell lines |
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A.
Letsch (D): |
T
cell monitoring during vaccination against tumor-associated antigens |
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P.
Lee (US): |
Diversity
and Recognition Efficiency of T Cell Responses to Cancer |
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P.
Romero (CH): |
Monitoring
tumor antigen specific T-cell responses in cancer patients and clinical
trials of peptide-based vaccination |
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(Poster) |
M.
Frentsch (D): |
Antigen-reactive
CD154 expression facilitates analysis and isolation of the entire repertoire
of antigen-specific CD4+ T-cells |
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(Poster) |
S. De
Rosa (US): |
Simultaneous
examination of perforin, granzyme A and granzyme B in virus-specific T cells |
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20:00
– 22:00 |
Buffet
Dinner, Exhibits, Poster Session I (Odd-numbered posters) |
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Friday (8:00 – 17:00), January 28 |
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08:00 |
Poster
setup (Even-numbered posters) |
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08:30
– 10:10 |
Session 3: MHC
& TcR Binding Technologies (Part I) |
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Chairman:
F. Kern (D) |
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J.
Altman (US): |
Phenotypic
analysis of tetramer binding cells |
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R.
Volkmer-Engert (D): |
Synthetic
peptides and peptide mixtures for analysis of T-cell antigen recognition |
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D.
Busch (D): |
Ex
vivo analysis of early events during CD8+ memory T cell development using MHC
multimer technologies |
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10:10
– 10:30 |
Break
(coffee and tea at the exhibits) and poster viewing |
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10:30
– 11:30 |
Session 3: MHC
& TcR Binding Technologies (Part II) |
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Chairman:
F. Kern (D) |
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A.
Thomsen (DK): |
Profiling
the optimal anti-viral CD8+ T cell response using MHC dextramers |
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T.
Kuus-Reichel (US): |
Immune
monitoring using MHC tetramers: Potential clinical applications and practical
considerations |
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14:00
– 15:00 |
Partec
Tutorial: How
the immune system starts its second century, presented by A. Cossarizza (Univ.
of Modena); New perspectives for HIV monitoring: absolute volumetric counting
of lymphocytes, CD45, CD4 and CD8 cells and quantitative viral load measurements
by dedicated flow cytometry |
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15:00
– 16:00 |
DakoCytomation
Tutorial: Tdex
MHC Dextramers – Experiences and practical aspects in antigen specific
T-cell analysis |
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16:00
– 17:00 |
Poster
Viewing (coffee and tea at the exhibits) |
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Friday (Evening), January 28 |
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17:00
– 18:00 |
Session 4: B
cells |
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Chairman:
A. Lanzavecchia (CH) |
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N.
Baumgarth (US): |
Enumeration
of B cell responses by flow cytometry |
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A.
Lanzavecchia (CH): |
Analysis
of human B cell responses |
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18:00
– 19:30 |
Session 5: In
Vivo |
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Chairman:
A. Lanzavecchia (CH) |
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(Poster) |
T.
Bunde (D): |
The CD8
T-cell response to the Immediate-Early-1 protein correlates with protection
from CMV-disease in patients after heart or lung transplantation |
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R.
Sekaly (CA): |
Pathways
of memory T cell development |
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(Poster) |
M.
Betts (US): |
HIV-infected
long-term nonprogressors maintain polyfunctional HIV-specific CD8+ T cell
responses of diverse memory phenotypes |
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R.
Koup (US): |
Comparison
of antigen-specific responses between vaccines and natural infection |
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20:00
– 22:00 |
Buffet
Dinner, Exhibits, Poster Session II (Even-numbered posters) |
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Saturday, January 29 |
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08:30
– 10:10 |
Session 6: Infectious Diseases (Part I) |
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Chairman:
F. Manca (IT) |
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G.
Pantaleo (CH): |
Antiviral
memory T cell responses |
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B.
Autran (F): |
Antigen
specific T cell responses and HIV pathogenesis |
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F.
Kern (D): |
Inroads
into the phenotype and differentiation pathway of M. tuberculosis specific T
cells |
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10:10
– 10:30 |
Break
(coffee and tea at the exhibits) and poster viewing |
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10:30
– 11:30 |
Session 6: Infectious Diseases (Part II) |
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Chairman:
F. Manca (IT) |
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G.
Janossy (UK): |
Technical
developments to assess antigen-specific T cell responses in HIV and TB (co-)
infections – the clinical need for discriminating rapid tests. |
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H.
Maecker (US): |
CMV
and HIV-specific T cells in healthy individuals and HIV progressors |
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14:00
– 16:00 |
Beckman-Coulter
Tutorial: Novel technologies and
approaches in epitope discovery |
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16:00
– 17:00 |
Coffee
and tea at the exhibits |
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17:00
– 18:30 |
Session 7: Infectious Diseases (Part III) |
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Chairman:
L. Picker (US) |
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(Poster) |
G. Li
Pira (IT): |
Cocktails
of CD4 and CD8 peptides for measurement of CMV pp65 specific T cells and for
generation of established Th and CTL lines |
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D.
Douek (US): |
T cell
receptor recognition motifs govern immune escape by antigen mutation in acute
SIV infection |
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(Poster) |
D.
Price (US): |
Dissection
of clonal avidity relationships in antigen-specific CD8+ T cell populations
directly ex vivo |
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L. Picker
(US): |
Analysis
of T cell function in Simian Immunodeficiency Virus (SIV) infection: New
approaches using polychromatic flow cytometry |
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20:30
– 22:30 |
Gala Dinner |
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Sunday, January 30 |
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Depart |
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